Phytochemical study and evaluation of cytotoxicity, mutagenicity, cell cycle kinetics and gene expression of Bauhinia holophylla (Bong.) Steud. in HepG2 cells in vitro.

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作者： Diego Luis,Ribeiro ^[1] ; Heloísa Lizotti,Cilião ^[2] ; Ana Flávia Leal,Specian ^[2] ; Juliana Mara,Serpeloni ^[2] ; Marcelo Tempesta,De Oliveira ^[3] ; Eliana Aparecida,Varanda ^[2] ; Wagner,Vilegas ^[3] ; Luiz Leonardo,Saldanha ^[4] ; Wilner,Martínez-López ^[5] ; Anne Lígia,Dokkedal ^[6] ; Ilce Mara Syllos,Cólus ^[7]

作者单位： Department of General Biology, Biological Sciences Center, State University of Londrina - UEL, Rod Celso Garcia Cid PR 445, Km 380, University Campus, P.O. Box 6001, Londrina, PR, CEP 86057-970, Brazil. diegolb_7@hotmail.com. ^[1] Department of General Biology, Biological Sciences Center, State University of Londrina - UEL, Rod Celso Garcia Cid PR 445, Km 380, University Campus, P.O. Box 6001, Londrina, PR, CEP 86057-970, Brazil. ^[2] Department of Biological Sciences, Faculty of Pharmaceutical Sciences of Araraquara, São Paulo State University - UNESP, Araraquara, SP, Brazil. ^[3] Campus Litoral Paulista, São Paulo State University - UNESP, São Vicente, SP, Brazil. ^[4] Department of Biological Sciences, Faculty of Sciences of Bauru, São Paulo State University - UNESP, Bauru, SP, Brazil. ^[5] Department of Botany, Biosciences Institute, São Paulo State University - UNESP, Botucatu, SP, Brazil. ^[6] Institute of Biological Investigation Clemente Estable, Montevideo, Uruguay. ^[7]

关键词 Antimutagenic Flavonoids Flow cytometry Micronucleus RT-qPCR

DOI 10.1007/s10616-017-0173-5

PMID 29230630

发布时间 2019-11-20

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