SMG-1 inhibition by miR-192/-215 causes epithelial-mesenchymal transition in gastric carcinogenesis via activation of Wnt signaling.

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第一作者： Xiaojing,Zhang

第一单位： Department of Pathology, The Shenzhen University School of Medicine, Shenzhen, Guangdong, 518060, China.

作者： Xiaojing,Zhang ^[1] ; Yin,Peng ^[2] ; Yong,Huang ^[3] ; Mengting,Yang ^[1] ; Ruibin,Yan ^[4] ; Yanqiu,Zhao ^[1] ; Yulan,Cheng ^[1] ; Xi,Liu ^[5] ; Shiqi,Deng ^[5] ; Xianling,Feng ^[6] ; Huijuan,Lin ^[6] ; Huimin,Yu ^[1] ; Si,Chen ^[1] ; Zhenfu,Zhao ^[7] ; Shanni,Li ^[1] ; Kuan,Li ^[1] ; Liang,Wang ^[1] ; Yanjie,Wei ^[1] ; Zhendan,He ^[1] ; Xinmin,Fan ^[1] ; Stephen J,Meltzer ^[2] ; Song,Li ^[8] ; Zhe,Jin ^[3]

作者单位： Department of Pathology, The Shenzhen University School of Medicine, Shenzhen, Guangdong, 518060, China. ^[1] Shenzhen Key Laboratory of Micromolecule Innovatal Drugs, Shenzhen Key Laboratory of translational Medicine of Tumor, Guangdong Key Laboratory for Genome Stability & Disease Prevention, Shenzhen University School of Medicine, Shenzhen, Guangdong, China. ^[2] Guangdong Province Key Laboratory of Molecular Oncologic Pathology, Guangzhou, Guangdong, China. ^[3] Department of Pathology, Wuhan University School of Basic Medical Sciences, Hubei, China. ^[4] Laboratory of Chemical Genomics, The Shenzhen Graduate School of Peking University, Shenzhen, Guangdong, China. ^[5] Department of Medicine/GI Division, Johns Hopkins University, Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland. ^[6] Department of Pathology and Pathophysiology, The Guangzhou Medical University, Guangzhou, Guangdong, China. ^[7] Center for High Performance Computing, Shenzhen Institutes of Advanced Technology, Shenzhen, Guangdong, China. ^[8]

关键词 EMT SMG-1 Wnt signaling pathway gastric cancer miR-192/-215

主题词动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);上皮-间质转化(Epithelial-Mesenchymal Transition);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);男(雄)性(Male);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 裸(Mice, Nude);微RNAs(MicroRNAs);中年人(Middle Aged);寡核苷酸序列分析(Oligonucleotide Array Sequence Analysis);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);胃(Stomach);胃肿瘤(Stomach Neoplasms);存活率分析(Survival Analysis);组织阵列分析(Tissue Array Analysis);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)

DOI 10.1002/cam4.1237

PMID 29239144

发布时间 2022-03-18

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Cancer medicine

2018年7卷1期

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SMG-1 inhibition by miR-192/-215 causes epithelial-mesenchymal transition in gastric carcinogenesis via activation of Wnt signaling.

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SMG-1 inhibition by miR-192/-215 causes epithelial-mesenchymal transition in gastric carcinogenesis via activation of Wnt signaling.

Cancer medicine

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Cancer medicine

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