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Loss of MTAP expression is a negative prognostic marker in Ewing sarcoma family of tumors.

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第一作者： Lucas Faria,Abrahao-Machado

第一单位： Department of Pathology & Molecular Diagnosis, Barretos Cancer Hospital, Barretos, SP, Brazil.

作者： Lucas Faria,Abrahao-Machado ^[1] ; Bruno,Antunes ^[2] ; Renee Zon,Filippi ^[3] ; Sahlua,Volc ^[4] ; Erica,Boldrini ^[5] ; Weder P,Menezes ^[6] ; Rui M,Reis ^[7] ; Olavo Pires,de Camargo ^[3]

作者单位： Department of Pathology & Molecular Diagnosis, Barretos Cancer Hospital, Barretos, SP, Brazil. ^[1] Department of Othopedics Surgery, Barretos Cancer Hospital, Barretos, SP, Brazil. ^[2] Institute of Orthopedics & Traumatology, Faculty of Medicine, University of São Paulo (FMUSP), São Paulo, SP, Brazil. ^[3] Oncology Department, Barretos Cancer Hospital, Barretos, SP, Brazil. ^[4] Pediatrics Department, Barretos Cancer Hospital, Barretos, SP, Brazil. ^[5] Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, SP, Brazil. ^[6] Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, SP, Brazil.;Life & Health Sciences Research Institute (ICVS), Health Sciences School, University of Minho, Braga, Portugal.;ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal. ^[7]

关键词 ESFT Ewing sarcoma family of tumors MTAP biomarkers methylthioadenosine phosphorylase prognosis