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首页> Chest> Asthma Is a Risk Factor for Respiratory Exacerbations Without Increased Rate of Lung Function Decline: Five-Year Follow-up in Adult Smokers From the COPDGene Study.

Asthma Is a Risk Factor for Respiratory Exacerbations Without Increased Rate of Lung Function Decline: Five-Year Follow-up in Adult Smokers From the COPDGene Study.

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作者： Lystra P,Hayden ^[1] ; Megan E,Hardin ^[2] ; Weiliang,Qiu ^[3] ; David A,Lynch ^[4] ; Matthew J,Strand ^[5] ; Edwin J,van Beek ^[6] ; James D,Crapo ^[7] ; Edwin K,Silverman ^[8] ; Craig P,Hersh ^[8] ; COPDGene Investigators(∗)

作者单位： Division of Respiratory Diseases, Boston Children's Hospital, Boston, MA; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA. Electronic address: lystra.hayden@childrens.harvard.edu. ^[1] Clinical Discovery Unit, Early Clinical Discovery, AstraZeneca, Waltham, MA. ^[2] Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA. ^[3] Department of Radiology, National Jewish Health, Denver, CO. ^[4] Division of Biostatistics and Bioinformatics, National Jewish Health, Denver, CO. ^[5] Department of Radiology, University of Edinburgh, Edinburgh, Scotland. ^[6] Division of Pulmonary, Critical Care, and Sleep Medicine, National Jewish Health, Denver, CO. ^[7] Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA. ^[8]

关键词 COPD asthma-COPD overlap childhood asthma childhood pneumonia respiratory exacerbations

主题词老年人(Aged);老年人, 80以上(Aged, 80 and over);哮喘(Asthma);儿童(Child);疾病恶化(Disease Progression);女(雌)性(Female);随访研究(Follow-Up Studies);用力呼气量(Forced Expiratory Volume);人类(Humans);线性模型(Linear Models);男(雄)性(Male);中年人(Middle Aged);肺疾病, 慢性阻塞性(Pulmonary Disease, Chronic Obstructive);呼吸功能不全(Respiratory Insufficiency);危险因素(Risk Factors)

DOI 10.1016/j.chest.2017.11.038

PMID 29248621

发布时间 2021-03-10

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