Genetic variant repressing ADH1A expression confers susceptibility to esophageal squamous-cell carcinoma.

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作者： Qionghua,Cui ^[1] ; Linna,Peng ^[1] ; Lixuan,Wei ^[1] ; Jiang,Chang ^[2] ; Wenle,Tan ^[1] ; Yingying,Luo ^[1] ; Xudong,Huang ^[1] ; Yanjie,Zhao ^[1] ; Jun,Li ^[1] ; Jiahui,Chu ^[1] ; Mingming,Shao ^[1] ; Chao,Zhang ^[3] ; Cheng,Li ^[3] ; Wen,Tan ^[1] ; Dongxin,Lin ^[4] ; Chen,Wu ^[5]

作者单位： National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. ^[1] Key Laboratory for Environment and Health (Ministry of Education), School of Public Health, Huazhong University of Science and Technology, Wuhan, China. ^[2] School of Life Sciences, Peking University, Beijing, China. ^[3] National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China. ^[4] National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Electronic address: chenwu@cicams.ac.cn. ^[5]

关键词 Alcohol drink Esophageal cancer Polymorphism eQTL

主题词食管肿瘤(Esophageal Neoplasms);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);疾病遗传易感性(Genetic Predisposition to Disease);全基因组关联研究(Genome-Wide Association Study);基因型(Genotype);人类(Humans);后叶激素运载蛋白类(Neurophysins);多态性, 单核苷酸(Polymorphism, Single Nucleotide);蛋白质前体(Protein Precursors);血管升压素类(Vasopressins)

DOI 10.1016/j.canlet.2017.12.020

PMID 29248712

发布时间 2019-04-22

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Genetic variant repressing ADH1A expression confers susceptibility to esophageal squamous-cell carcinoma.

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Genetic variant repressing ADH1A expression confers susceptibility to esophageal squamous-cell carcinoma.

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