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Synthesis and biological evaluation of novel doxorubicin-containing ASGP-R-targeted drug-conjugates.

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第一作者： Yan A,Ivanenkov

第一单位： Lomonosov Moscow State University, Chemistry Dept, Leninskie Gory, Building 1/3, GSP-1, Moscow 119991, Russian Federation; Moscow Institute of Physics and Technology (State University), 9 Institutskiy lane, Dolgoprudny City, Moscow Region 141700, Russian Federation; National University of Science and Technology MISiS, 9 Leninskiy pr, Moscow, 119049, Russian Federation; Institute of Biochemistry and Genetics Russian Academy of Science (IBG RAS) Ufa Scientific Centre, Oktyabrya Prospekt 71, 450054 Ufa, Russian Federation. Electronic address: yai@chemdiv.com.

作者： Yan A,Ivanenkov ^[1] ; Alexander G,Majouga ^[2] ; Rostislav A,Petrov ^[3] ; Stanislav A,Petrov ^[3] ; Sergey V,Kovalev ^[3] ; Svetlana Yu,Maklakova ^[3] ; Emil Yu,Yamansarov ^[3] ; Irina V,Saltykova ^[3] ; Ekaterina V,Deyneka ^[4] ; Gleb I,Filkov ^[4] ; Victor E,Kotelianski ^[5] ; Timofey S,Zatsepin ^[6] ; Elena K,Beloglazkina ^[3]

作者单位： Lomonosov Moscow State University, Chemistry Dept, Leninskie Gory, Building 1/3, GSP-1, Moscow 119991, Russian Federation; Moscow Institute of Physics and Technology (State University), 9 Institutskiy lane, Dolgoprudny City, Moscow Region 141700, Russian Federation; National University of Science and Technology MISiS, 9 Leninskiy pr, Moscow, 119049, Russian Federation; Institute of Biochemistry and Genetics Russian Academy of Science (IBG RAS) Ufa Scientific Centre, Oktyabrya Prospekt 71, 450054 Ufa, Russian Federation. Electronic address: yai@chemdiv.com. ^[1] Lomonosov Moscow State University, Chemistry Dept, Leninskie Gory, Building 1/3, GSP-1, Moscow 119991, Russian Federation; National University of Science and Technology MISiS, 9 Leninskiy pr, Moscow, 119049, Russian Federation; Dmitry Mendeleev University of Chemical Technology of Russia, Miusskaya sq. 9, Moscow, 125047, Russian Federation. ^[2] Lomonosov Moscow State University, Chemistry Dept, Leninskie Gory, Building 1/3, GSP-1, Moscow 119991, Russian Federation. ^[3] Moscow Institute of Physics and Technology (State University), 9 Institutskiy lane, Dolgoprudny City, Moscow Region 141700, Russian Federation. ^[4] Skolkovo Institute of Science and Technology, 100 Novaya st., 143025 Skolkovo, Russian Federation. ^[5] Lomonosov Moscow State University, Chemistry Dept, Leninskie Gory, Building 1/3, GSP-1, Moscow 119991, Russian Federation; Skolkovo Institute of Science and Technology, 100 Novaya st., 143025 Skolkovo, Russian Federation; Lomonosov Moscow State University, A.N. Belozersky Institute of Physico-Chemical Biology, Leninskye gory, house 1, building 40, Moscow, 119992, Russian Federation. ^[6]

关键词 ASGP-R Cancer Doxorubicin Targeted drug delivery