X-linked inhibitor of apoptosis protein (XIAP) is a client of heat shock protein 70 (Hsp70) and a biomarker of its inhibition.

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作者： Laura C,Cesa ^[1] ; Hao,Shao ^[2] ; Sharan R,Srinivasan ^[1] ; Eric,Tse ^[3] ; Chetali,Jain ^[4] ; Erik R P,Zuiderweg ^[5] ; Daniel R,Southworth ^[3] ; Anna K,Mapp ^[1] ; Jason E,Gestwicki ^[3]

作者单位： From the Program in Chemical Biology. ^[1] the Department of Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, California 94158. ^[2] Biological Chemistry, and. ^[3] The Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109 and. ^[4] Departments of Chemistry and. ^[5] the Department of Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, California 94158 Jason.gestwicki@ucsf.edu. ^[6]

关键词 cancer biology chaperone chemical biology heat shock protein 90 (Hsp90)protein–protein interaction

主题词细胞系, 肿瘤(Cell Line, Tumor);HSP70热休克蛋白质类(HSP70 Heat-Shock Proteins);HSP90热休克蛋白质类(HSP90 Heat-Shock Proteins);人类(Humans);蛋白质结合(Protein Binding);X连锁凋亡抑制蛋白质(X-Linked Inhibitor of Apoptosis Protein)

DOI 10.1074/jbc.RA117.000634

PMID 29255093

发布时间 2021-12-04

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