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Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders.

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第一作者: Hoang T,Nguyen
第一单位: Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA. tan-hoang.nguyen@mssm.edu.
作者单位: Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA. tan-hoang.nguyen@mssm.edu. [1] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. [2] Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.;Department of Surgery, Massachusetts General Hospital, Boston, 02114, MA, USA. [3] Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA.;Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA. [4] Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA. [5] Laboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, SE-17177, Sweden. [6] Division of Genetic Medicine, Departments of Medicine, Psychiatry and Biomedical Informatics, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, 37235, TN, USA. [7] Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.;Department of Genetics, Harvard Medical School, Cambridge, Massachusetts, USA. [8] Verily Life Sciences, 269 E Grand Ave, South San Francisco, 94080, CA, USA. [9] Seaver Autism Center, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA. [10] Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA.;Seaver Autism Center, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA.;The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA.;Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA. [11] Department of Functional Genomics, The Center for Neurogenomics and Cognitive Research, VU University and VU Medical Center, Amsterdam, The Netherlands. [12] Department of Molecular and Cellular Neurobiology, The Center for Neurogenomics and Cognitive Research, VU University, Amsterdam, The Netherlands. [13] Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA.;Sleep Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. [14] Department of Human Genetics, University of Chicago, Chicago, 60637, IL, USA. [15] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.;Departments of Genetics and Psychiatry, University of North Carolina, Chapel Hill, 27599-7264, North Carolina, USA. [16] Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA. eli.stahl@mssm.edu.;Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. eli.stahl@mssm.edu. [17]
DOI 10.1186/s13073-017-0497-y
PMID 29262854
发布时间 2023-11-12
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