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Anti-aging factor, serum alpha-Klotho, as a marker of acute physiological stress, and a predictor of ICU mortality, in patients with septic shock.

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第一作者： Peter A,Abdelmalik

第一单位： Department of Neurology, State University of New York, University at Buffalo, Buffalo, NY 14202, United States. Electronic address: peterabd@buffalo.edu.

作者： Peter A,Abdelmalik ^[1] ; Robert D,Stevens ^[2] ; Sarabdeep,Singh ^[3] ; John,Skinner ^[3] ; J Ricardo,Carhuapoma ^[4] ; Sanjeev,Noel ^[5] ; Roger,Johns ^[3] ; Ralph J,Fuchs ^[6]

作者单位： Department of Neurology, State University of New York, University at Buffalo, Buffalo, NY 14202, United States. Electronic address: peterabd@buffalo.edu. ^[1] Department of Anesthesia and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States; Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States; Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States. ^[2] Department of Anesthesia and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States. ^[3] Department of Anesthesia and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States; Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States. ^[4] Division of Nephrology, Department of Medicine, The Johns Hopkins University, Baltimore, MD 21287, United States. ^[5] Department of Anaesthesiology, The University of Auckland, Grafton, Auckland, New Zealand; Hauora Tairāwhiti District Health Board, Gisborne 4040, New Zealand. ^[6]

关键词 Acute physiology Biomarker Frailty Longevity Resilience Senescence Sepsis