Mutant selection window of four quinolone antibiotics against clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis.

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第一作者： Hajime,Nakai

第一单位： Division of Clinical Infection Diseases & Chemotherapy, Tohoku Medical and Pharmaceutical University, Sendai, Japan; Department of Pharmacy, Tohoku-Rosai Hospital, Sendai, Japan.

作者： Hajime,Nakai ^[1] ; Takumi,Sato ^[2] ; Takashi,Uno ^[2] ; Emiko,Furukawa ^[2] ; Masato,Kawamura ^[2] ; Hiroshi,Takahashi ^[3] ; Akira,Watanabe ^[4] ; Shigeru,Fujimura ^[5]

作者单位： Division of Clinical Infection Diseases & Chemotherapy, Tohoku Medical and Pharmaceutical University, Sendai, Japan; Department of Pharmacy, Tohoku-Rosai Hospital, Sendai, Japan. ^[1] Division of Clinical Infection Diseases & Chemotherapy, Tohoku Medical and Pharmaceutical University, Sendai, Japan. ^[2] Department of Respiratory Medicine, Saka General Hospital, Sendai, Japan. ^[3] Research Division for Development of Anti-infective Agents, Institute of Development Aging and Cancer, Tohoku University, Sendai, Japan. ^[4] Division of Clinical Infection Diseases & Chemotherapy, Tohoku Medical and Pharmaceutical University, Sendai, Japan; Research Division for Development of Anti-infective Agents, Institute of Development Aging and Cancer, Tohoku University, Sendai, Japan. Electronic address: sfuji@tohoku-mpu.ac.jp. ^[5]

关键词 Haemophilus influenzae Moraxella catarrhalis Mutant selection window Quinolone resistance-determining region Streptococcus pneumoniae