A cell-penetrating whole molecule antibody targeting intracellular HBx suppresses hepatitis B virus via TRIM21-dependent pathway.

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第一作者： Jun-Fang,Zhang

第一单位： State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China.;National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Science, Xiamen University, Xiamen 361102, China.;School of Medicine, Shenzhen University, Shenzhen, 518060, China.

作者： Jun-Fang,Zhang ^[1] ; Hua-Long,Xiong ^[2] ; Jia-Li,Cao ^[2] ; Shao-Juan,Wang ^[2] ; Xue-Ran,Guo ^[2] ; Bi-Yun,Lin ^[3] ; Ying,Zhang ^[2] ; Jing-Hua,Zhao ^[2] ; Ying-Bin,Wang ^[2] ; Tian-Ying,Zhang ^[2] ; Quan,Yuan ^[2] ; Jun,Zhang ^[2] ; Ning-Shao,Xia ^[2]

作者单位： State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China.;National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Science, Xiamen University, Xiamen 361102, China.;School of Medicine, Shenzhen University, Shenzhen, 518060, China. ^[1] State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China.;National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Science, Xiamen University, Xiamen 361102, China. ^[2] Department of Clinical Pathology, Affiliated Hospital of Guangdong Medical College, Zhanjiang, 524001, China. ^[3]

关键词 Hepatitis B virus X protein antibodies for intracellular targets antibody-mediated intracellular immunity cell-penetrating peptide hepatitis B virus