WEE1 epigenetically modulates 5-hmC levels by pY37-H2B dependent regulation of <i>IDH2</i> gene expression.

导出 OA

翻译打印收藏纠错

第一作者： Nupam P,Mahajan

第一单位： Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA.;Department of Oncological Sciences, University of South Florida, Tampa, FL 33612, USA.

作者： Nupam P,Mahajan ^[1] ; Pavani,Malla ^[2] ; Shambhavi,Bhagwat ^[2] ; Vasundhara,Sharma ^[2] ; Amod,Sarnaik ^[3] ; Jongphil,Kim ^[4] ; Shari,Pilon-Thomas ^[5] ; Jeffery,Weber ^[6] ; Kiran,Mahajan ^[7]

作者单位： Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA.;Department of Oncological Sciences, University of South Florida, Tampa, FL 33612, USA. ^[1] Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA. ^[2] Department of Cutaneous Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA. ^[3] Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, FL 33612, USA.;Department of Oncological Sciences, University of South Florida, Tampa, FL 33612, USA. ^[4] Department of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA. ^[5] Laura and Isaac Perlmutter Cancer Center, NYU Langone Medical Center, New York, NY 10016, USA. ^[6] Department of Tumor Biology, Moffitt Cancer Center, Tampa, FL 33612, USA.;Department of Oncological Sciences, University of South Florida, Tampa, FL 33612, USA. ^[7]

关键词 IDH2 WEE1 histone H2B tyrosine kinase tyrosine phosphorylation

DOI 10.18632/oncotarget.22374

PMID 29290954

发布时间 2019-11-20

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交