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Mechanisms of disordered neurodegenerative function: concepts and facts about the different roles of the protein kinase RNA-like endoplasmic reticulum kinase (PERK).

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第一作者： Yasmeen M,Taalab

第一单位： Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Al-Mansoura University, Al-Mansoura, 35111, Egypt.

作者： Yasmeen M,Taalab ^[1] ; Nour,Ibrahim ^[2] ; Ahmed,Maher ^[3] ; Mubashir,Hassan ^[4] ; Wael,Mohamed ^[5] ; Ahmed A,Moustafa ^[6] ; Mohamed,Salama ^[7] ; Dina,Johar ^[8] ; Larry,Bernstein ^[9]

作者单位： Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Al-Mansoura University, Al-Mansoura, 35111, Egypt. ^[1] Faculty of Medicine, Ain Shams University, Cairo, 11591, Egypt. ^[2] Zoonotic Disease Department, National Research Center, Dokki, Giza, 25200, Egypt. ^[3] Department of Biological Sciences, College of Natural Sciences, Kongju National University, Gongju-do 32588, South Korea. ^[4] Department of Clinical Pharmacology, Faculty of Medicine, Al-Menoufia University, Al-Menoufia, 25200 Egypt.;Basic Medical Science Department, Kulliyyah of Medicine, International Islamic University Malaysia, Kunatan Pahang, Malaysia. ^[5] School of Social Sciences and Psychology and MARCS Institute for Brain and Behaviour, Western Sydney University, Sydney, New South Wales, 2751 Australia. ^[6] Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Al-Mansoura University, Al-Mansoura, 35111, Egypt.;Medical Experimental Research Center (MERC), Al-Mansoura University, Al-Mansoura, Egypt. ^[7] Department of Biochemistry and Nutrition, Faculty of Women for Arts, Sciences and Education, Ain Shams University, Heliopolis, Cairo, 11291, Egypt.;Max Rady College of Medicine, Rady Faculty of Health Sciences, Department of Physiology & Pathophysiology 432 Basic Medical Sciences Building, 745 Bannatyne Avenue University of Manitoba, Winnipeg, MB R3E 0J9, Canada, e-mail:umjohar@myumanitoba.ca. ^[8] Triplex Consulting, 54 Firethorn Lane, Northampton, MA 01060, USA. ^[9]

关键词 apoptosis autophagy endoplasmic reticulum stress mitochondrial stress unfolded protein response