首页> Oncotarget> Metformin sensitizes lung cancer cells to treatment by the tyrosine kinase inhibitor erlotinib.

Metformin sensitizes lung cancer cells to treatment by the tyrosine kinase inhibitor erlotinib.

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第一作者： Xiaofei,Wang

第一单位： Department of Respiratory and Critical Care Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.;Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.

作者： Xiaofei,Wang ^[1] ; Keqiang,Chen ^[2] ; Ying,Yu ^[3] ; Yi,Xiang ^[4] ; Jae Hong,Kim ^[2] ; Wanghua,Gong ^[5] ; Jiaqiang,Huang ^[6] ; Guochao,Shi ^[4] ; Qingyun,Li ^[4] ; Min,Zhou ^[4] ; Thomas,Sayers ^[5] ; Poonam,Tewary ^[5] ; Beili,Gao ^[4] ; Ji Ming,Wang ^[2]

作者单位： Department of Respiratory and Critical Care Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.;Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA. ^[1] Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA. ^[2] Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.;Eye Institute, Affiliated Hospital of Nantong University, Nantong 226001, China. ^[3] Department of Respiratory and Critical Care Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China. ^[4] Basic Research Program, Leidos Biomedical Research, Inc., Frederick, MD 21702, USA. ^[5] College of Life Sciences and Bioengineering, School of Sciences, Beijing Jiaoton University, Beijing 100044, China. ^[6]

关键词 EGFR erlotinib lung cancer metformin phosphorylation

DOI 10.18632/oncotarget.22596

PMID 29312591

发布时间 2025-05-29

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