Tanshinone IIA induces cell death via Beclin-1-dependent autophagy in oral squamous cell carcinoma SCC-9 cell line.

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作者： Ye,Qiu ^[1] ; Conghua,Li ^[1] ; Qinhua,Wang ^[1] ; Xingqi,Zeng ^[1] ; Ping,Ji ^[1]

作者单位： Stomatological Hospital of Chongqing Medical University, North Songshi Road #426, Chongqing, 401147, China. ^[1] Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, North Songshi Road #426, Chongqing, 401147, China. ^[2] Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, North Songshi Road #426, Chongqing, 401147, China. ^[3]

关键词 mTOR Akt Atg12-Atg5 Atg7 Beclin-1 PI3K autophagy oral squamous cell carcinoma tanshinone IIA

主题词动物(Animals);抗肿瘤药, 植物(Antineoplastic Agents, Phytogenic);细胞凋亡(Apoptosis);自噬(Autophagy);癌, 鳞状细胞(Carcinoma, Squamous Cell);细胞增殖(Cell Proliferation);人类(Humans);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 裸(Mice, Nude);口腔肿瘤(Mouth Neoplasms);肿瘤细胞, 培养的(Tumor Cells, Cultured);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)

DOI 10.1002/cam4.1281

PMID 29316373

发布时间 2022-04-09

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Cancer medicine

2018年7卷2期

397-407页

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Tanshinone IIA induces cell death via Beclin-1-dependent autophagy in oral squamous cell carcinoma SCC-9 cell line.

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Tanshinone IIA induces cell death via Beclin-1-dependent autophagy in oral squamous cell carcinoma SCC-9 cell line.

Cancer medicine

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Cancer medicine

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