ARID5B as a critical downstream target of the TAL1 complex that activates the oncogenic transcriptional program and promotes T-cell leukemogenesis.

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第一作者： Wei Zhong,Leong

第一单位： Cancer Science Institute of Singapore, National University of Singapore, 117599 Singapore.

作者： Wei Zhong,Leong ^[1] ; Shi Hao,Tan ^[1] ; Phuong Cao Thi,Ngoc ^[1] ; Stella,Amanda ^[1] ; Alice Wei Yee,Yam ^[1] ; Wei-Siang,Liau ^[1] ; Zhiyuan,Gong ^[2] ; Lee N,Lawton ^[1] ; Daniel G,Tenen ^[3] ; Takaomi,Sanda ^[4]

作者单位： Cancer Science Institute of Singapore, National University of Singapore, 117599 Singapore. ^[1] Department of Biological Sciences, National University of Singapore, 117543 Singapore. ^[2] Cancer Science Institute of Singapore, National University of Singapore, 117599 Singapore.;Harvard Medical School, Boston, Massachusetts 02215, USA.;Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 117599 Singapore. ^[3] Cancer Science Institute of Singapore, National University of Singapore, 117599 Singapore.;Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 117599 Singapore. ^[4]

关键词 ARID5B MYC T-cell acute lymphoblastic leukemia TAL1 core regulatory circuit