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首页> Cellular signalling> LPA-induced migration of ovarian cancer cells requires activation of ERM proteins via LPA<sub>1</sub> and LPA<sub>2</sub>.

LPA-induced migration of ovarian cancer cells requires activation of ERM proteins via LPA<sub>1</sub> and LPA<sub>2</sub>.

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作者： Jeongrak,Park ^[1] ; Jin-Hyeok,Jang ^[1] ; Seojin,Oh ^[1] ; Minhye,Kim ^[1] ; Changhoon,Shin ^[1] ; Minseok,Jeong ^[1] ; Kyun,Heo ^[2] ; Jong Bae,Park ^[3] ; Sang Ryong,Kim ^[4] ; Yong-Seok,Oh ^[5]

作者单位： Department of Brain-Cognitive Sciences, Daegu-Gyeongbuk Institute of Science and Technology (DGIST), Hyeonpung-myeon, Dalseong-gun, Daegu, Republic of Korea. ^[1] Research Institute, National Cancer Center, Goyang, Republic of Korea. ^[2] Research Institute, National Cancer Center, Goyang, Republic of Korea; Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Republic of Korea. ^[3] School of Life Sciences, BK21 plus KNU Creative BioResearch Group, Institute of Life Science & Biotechnology, Kyungpook National University, Daegu 41566, Republic of Korea. ^[4] Department of Brain-Cognitive Sciences, Daegu-Gyeongbuk Institute of Science and Technology (DGIST), Hyeonpung-myeon, Dalseong-gun, Daegu, Republic of Korea. Electronic address: ysoh2040@dgist.ac.kr. ^[5]

关键词 Cell migration ERM (ezrin/radixin/moesin) proteins LPA receptor Lysophosphatidic acid (LPA)Ovarian cancer RhoA

主题词细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);细胞支架蛋白质类(Cytoskeletal Proteins);女(雌)性(Female);人类(Humans);溶血磷脂素类(Lysophospholipids);膜蛋白质类(Membrane Proteins);微丝蛋白质类(Microfilament Proteins);卵巢肿瘤(Ovarian Neoplasms);磷酰化(Phosphorylation);受体, 溶血磷脂酸(Receptors, Lysophosphatidic Acid);信号传导(Signal Transduction);ρA GTP结合蛋白质(rhoA GTP-Binding Protein)

DOI 10.1016/j.cellsig.2018.01.007

PMID 29329782

发布时间 2022-04-09

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Cellular signalling

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