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首页> Nature communications> Mechanically-sensitive miRNAs bias human mesenchymal stem cell fate via mTOR signalling.

Mechanically-sensitive miRNAs bias human mesenchymal stem cell fate via mTOR signalling.

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作者： Jessica E,Frith ^[1] ; Gina D,Kusuma ^[2] ; James,Carthew ^[3] ; Fanyi,Li ^[3] ; Nicole,Cloonan ^[3] ; Guillermo A,Gomez ^[4] ; Justin J,Cooper-White ^[5]

作者单位： Materials Science and Engineering, Monash University, Clayton, VIC, 3800, Australia. Jessica.Frith@monash.edu. ^[1] Australian Institute for Bioengineering and Nanotechnology, University of Queensland, St Lucia, 3072, Australia. Jessica.Frith@monash.edu. ^[2] Materials Science and Engineering, Monash University, Clayton, VIC, 3800, Australia. ^[3] School of Biological Sciences, The University of Auckland, Auckland Central, Auckland, 1010, New Zealand. ^[4] Centre for Cancer Biology, SA Pathology and the University of South Australia, Frome Road, Adelaide, 5000, SA, Australia. ^[5] Institute for Molecular Bioscience, Cell Biology, University of Queensland, St Lucia, QLD, 3072, Australia. ^[6] Australian Institute for Bioengineering and Nanotechnology, University of Queensland, St Lucia, 3072, Australia. ^[7] School of Chemical Engineering, University of Queensland, St Lucia, QLD, 3072, Australia. ^[8] Biomedical Manufacturing Manufacturing Flagship, CSIRO, Clayton, VIC, 3169, Australia. ^[9]

主题词细胞分化(Cell Differentiation);细胞增殖(Cell Proliferation);细胞, 培养的(Cells, Cultured);基因表达调控(Gene Expression Regulation);人类(Humans);水凝胶类(Hydrogels);动力传导, 细胞(Mechanotransduction, Cellular);间质干细胞(Mesenchymal Stem Cells);微RNAs(MicroRNAs);显微镜检查, 共焦(Microscopy, Confocal);骨生成(Osteogenesis);信号传导(Signal Transduction);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases);组织工程(Tissue Engineering)

DOI 10.1038/s41467-017-02486-0

PMID 29343687

发布时间 2021-12-04

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Nature communications

Nature communications

2018年9卷1期

257页

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