Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase.

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第一作者： Danqing,Feng

第一单位： Medicinal Chemistry, PPDM Preclinical ADME, In Vitro Pharmacology, In Vivo Pharmacology, and Biology-Discovery Departments, Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.

作者： Danqing,Feng ^[1] ; Tesfaye,Biftu ^[1] ; F Anthony,Romero ^[1] ; Ahmet,Kekec ^[1] ; James,Dropinski ^[1] ; Andrew,Kassick ^[1] ; Shiyao,Xu ^[1] ; Marc M,Kurtz ^[1] ; Anantha,Gollapudi ^[1] ; Qing,Shao ^[1] ; Xiaodong,Yang ^[1] ; Ku,Lu ^[1] ; Gaochao,Zhou ^[1] ; Daniel,Kemp ^[1] ; Robert W,Myers ^[1] ; Hong-Ping,Guan ^[1] ; Maria E,Trujillo ^[1] ; Cai,Li ^[1] ; Ann,Weber ^[1] ; Iyassu K,Sebhat ^[1]

作者单位： Medicinal Chemistry, PPDM Preclinical ADME, In Vitro Pharmacology, In Vivo Pharmacology, and Biology-Discovery Departments, Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States. ^[1]

DOI 10.1021/acsmedchemlett.7b00417

PMID 29348809

发布时间 2020-09-30

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ACS medicinal chemistry letters

2018年9卷1期

39-44页

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Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase.

ACS medicinal chemistry letters

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ACS medicinal chemistry letters

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Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase.

ACS medicinal chemistry letters

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ACS medicinal chemistry letters

相关期刊

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