Natural product andrographolide alleviated APAP-induced liver fibrosis by activating Nrf2 antioxidant pathway.
第一作者:
Hongyu,Yan
第一单位:
The MOE Key Laboratory for Standardization of Chinese Medicines, Shanghai Key Laboratory of Compound Chinese Medicines and The SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
作者:
主题词
醋氨酚(Acetaminophen);动物(Animals);抗氧化剂(Antioxidants);胶原(Collagen);二萜类(Diterpenes);肝星状细胞(Hepatic Stellate Cells);羟脯氨酸(Hydroxyproline);脂质过氧化作用(Lipid Peroxidation);肝(Liver);肝硬化(Liver Cirrhosis);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);NF-E2相关因子2(NF-E2-Related Factor 2);蛋白质转运(Protein Transport);活性氧(Reactive Oxygen Species)
DOI
10.1016/j.tox.2018.01.007
PMID
29355602
发布时间
2018-11-19
- 浏览3
Toxicology
1-12页
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