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Regional and subtype-dependent miRNA signatures in sporadic Creutzfeldt-Jakob disease are accompanied by alterations in miRNA silencing machinery and biogenesis.

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第一作者: Franc,Llorens
第一单位: Department of Neurology, University Medical School, Göttingen, Germany.;Center for Networked Biomedical Research on Neurodegenerative Diseases (CIBERNED), Barcelona, Spain.
作者单位: Department of Neurology, University Medical School, Göttingen, Germany.;Center for Networked Biomedical Research on Neurodegenerative Diseases (CIBERNED), Barcelona, Spain. [1] Department of Neurology, University Medical School, Göttingen, Germany.;German Center for Neurodegenerative Diseases (DZNE), Translational Studies and Biomarkers, Göttingen, Germany. [2] Centre for Genomic Regulation, Barcelona, Spain. [3] Prion Diseases Research Group, School of Health Sciences, Department Of Pharmacy, Aristotle University of Thessaloniki, Thessaloniki, Greece. [4] Department of Genetics, Development and Molecular Biology, School of Biology, Aristotle University of Thessaloniki, Thessaloniki, Greece. [5] Center for Networked Biomedical Research on Neurodegenerative Diseases (CIBERNED), Barcelona, Spain. [6] Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain. [7] German Center for Neurodegenerative Diseases (DZNE), Computational Systems Biology, Göttingen, Germany. [8] Department of Neurology, University Medical School, Göttingen, Germany. [9] Centro de Investigación en Sanidad Animal (CISA-INIA), Madrid, Spain. [10] Institut National de la Recherche Agronomique/Ecole Nationale Vétérinaire, Toulouse, France. [11] Center for Networked Biomedical Research on Neurodegenerative Diseases (CIBERNED), Barcelona, Spain.;Molecular and Cellular Neurobiotechnology, Catalonian Institute for Bioengineering (IBEC), Parc Científic de Barcelona, Barcelona, Spain.;Department of Cell Biology, University of Barcelona, Barcelona, Spain. [12] Molecular Virology group, Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain. [13] German Center for Neurodegenerative Diseases (DZNE), Epigenetics and Systems Medicine in Neurodegenerative Diseases, Göttingen, Germany. [14] German Center for Neurodegenerative Diseases (DZNE), Computational Systems Biology, Göttingen, Germany.;German Center for Neurodegenerative Diseases (DZNE), Tuebingen, Germany.;Center for Molecular Neurobiology University Medical Center Hamburg-Eppendorf, Hamburg, Germany. [15] Center for Networked Biomedical Research on Neurodegenerative Diseases (CIBERNED), Barcelona, Spain.;Senior consultant, Bellvitge University Hospital-IDIBELL, Department of Pathology and Experimental Therapeutics, University of Barcelona, Hospitalet de Llobregat, Barcelona, Spain. [16]
DOI 10.1371/journal.ppat.1006802
PMID 29357384
发布时间 2024-03-13
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