Antitumor effects of Tubeimoside-1 in NCI-H1299 cells are mediated by microRNA-126-5p-induced inactivation of VEGF-A/VEGFR-2/ERK signaling pathway.
作者:
主题词
成年人(Adult);老年人(Aged);抗肿瘤药, 植物(Antineoplastic Agents, Phytogenic);细胞凋亡(Apoptosis);癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);葫芦科(Cucurbitaceae);中草药(Drugs, Chinese Herbal);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);氢醌类(Hydroquinones);肺肿瘤(Lung Neoplasms);MAP激酶信号系统(MAP Kinase Signaling System);男(雄)性(Male);微RNAs(MicroRNAs);中年人(Middle Aged);丝裂原活化蛋白激酶1(Mitogen-Activated Protein Kinase 1);丝裂原活化蛋白激酶3(Mitogen-Activated Protein Kinase 3);皂苷类(Saponins);三萜类(Triterpenes);血管内皮生长因子A(Vascular Endothelial Growth Factor A);血管内皮生长因子受体2(Vascular Endothelial Growth Factor Receptor-2)
DOI
10.3892/mmr.2018.8459
PMID
29363720
发布时间
2021-10-25
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Molecular medicine reports
4327-4336页
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