Reversed isoniazids: Design, synthesis and evaluation against Mycobacterium tuberculosis.

导出原文传递

翻译打印收藏纠错

第一作者： Malkeet,Kumar

第一单位： Department of Chemistry, University of Cape Town, Rondebosch, 7701, South Africa.

作者： Malkeet,Kumar ^[1] ; Kawaljit,Singh ^[1] ; Andile H,Ngwane ^[2] ; Fahreta,Hamzabegovic ^[3] ; Getahun,Abate ^[3] ; Bienyameen,Baker ^[2] ; Ian,Wiid ^[2] ; Daniel F,Hoft ^[4] ; Peter,Ruminski ^[5] ; Kelly,Chibale ^[6]

作者单位： Department of Chemistry, University of Cape Town, Rondebosch, 7701, South Africa. ^[1] DST-NRF Centre of Excellence for Biomedical Tuberculosis Research, SAMRC Centre for TB Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, P.O. Box 241, Cape Town 8000, South Africa. ^[2] Department of Internal Medicine, Division of Infectious Diseases, Allergy and Immunology, Saint Louis University, 1100 S. Grand Blvd, 63104 MO, USA. ^[3] Department of Internal Medicine, Division of Infectious Diseases, Allergy and Immunology, Saint Louis University, 1100 S. Grand Blvd, 63104 MO, USA; Department of Molecular Biology, Saint Louis University, 1100 S. Grand Blvd, 63104 MO, USA. ^[4] Centre for World Health and Medicine, Saint Louis University, 1100 S. Grand Blvd, 63104 MO, USA. ^[5] Department of Chemistry, University of Cape Town, Rondebosch, 7701, South Africa; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Rondebosch, 7701, South Africa; South African Medical Research Council Drug Discovery and Development Research Unit, Department of Chemistry, University of Cape Town, Rondebosch, 7701, South Africa. Electronic address: kelly.chibale@uct.ac.za. ^[6]

关键词 Chemosensitizers Efflux pump inhibitors Efflux pumps Ethidium bromide M. tuberculosis Macrophages