Glutathione-PEGylated liposomal methylprednisolone in comparison to free methylprednisolone: slow release characteristics and prolonged lymphocyte depression in a first-in-human study.
第一作者:
K M S,Kanhai
第一单位:
Centre for Human Drug Research, Leiden, The Netherlands.
作者:
主题词
促肾上腺皮质激素(Adrenocorticotropic Hormone);成年人(Adult);抗变态反应药(Anti-Allergic Agents);消炎药(Anti-Inflammatory Agents);血糖(Blood Glucose);氯马斯汀(Clemastine);交叉研究(Cross-Over Studies);迟效制剂(Delayed-Action Preparations);剂量效应关系, 药物(Dose-Response Relationship, Drug);双盲法(Double-Blind Method);用药计划表(Drug Administration Schedule);药物调剂(Drug Compounding);药物疗法, 联合(Drug Therapy, Combination);女(雌)性(Female);谷胱甘肽(Glutathione);人类(Humans);脂质体(Liposomes);淋巴细胞计数(Lymphocyte Count);男(雄)性(Male);甲泼尼龙(Methylprednisolone);骨钙素(Osteocalcin);聚乙烯二醇类(Polyethylene Glycols)
DOI
10.1111/bcp.13525
PMID
29385232
发布时间
2021-01-09
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