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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy.

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第一作者： Matthew P,Goetz

第一单位： Department of Oncology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA.

作者： Matthew P,Goetz ^[1] ; Katrin,Sangkuhl ^[2] ; Henk-Jan,Guchelaar ^[3] ; Matthias,Schwab ^[4] ; Michael,Province ^[5] ; Michelle,Whirl-Carrillo ^[2] ; W Fraser,Symmans ^[6] ; Howard L,McLeod ^[7] ; Mark J,Ratain ^[8] ; Hitoshi,Zembutsu ^[9] ; Andrea,Gaedigk ^[10] ; Ron H,van Schaik ^[11] ; James N,Ingle ^[1] ; Kelly E,Caudle ^[12] ; Teri E,Klein ^[2]

作者单位： Department of Oncology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA. ^[1] Department of Biomedical Data Science, Stanford University, Stanford, California, USA. ^[2] Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, The Netherlands. ^[3] Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.;Department of Clinical Pharmacology, University Hospital, Tuebingen, Germany.;Department of Pharmacy and Biochemistry, University of Tuebingen, Tuebingen, Germany. ^[4] Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri, USA. ^[5] Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. ^[6] Moffitt Cancer Center, Tampa, Florida, USA. ^[7] Center for Personalized Therapeutics, University of Chicago, Chicago, Illinois, USA. ^[8] Division of Human Genetics, National Cancer Center, Research Institute, Tokyo, Japan. ^[9] Division of Clinical Pharmacology, Toxicology & Therapeutic Innovation, Children's Mercy Kansas City and Department of Pediatrics, University of Missouri-Kansas City, Kansas City, Missouri, USA. ^[10] International Expertcenter Pharmacogenetics, Dept Clinical Chemistry, Erasmus MC, Rotterdam, The Netherlands.;LKCH UMC Utrecht, The Netherlands. ^[11] Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA. ^[12]

医学主题词抗肿瘤药, 激素(Antineoplastic Agents, Hormonal);乳腺肿瘤(Breast Neoplasms);细胞色素P450 CYP2D6(Cytochrome P-450 CYP2D6);女(雌)性(Female);基因型(Genotype);人类(Humans);肿瘤复发, 局部(Neoplasm Recurrence, Local);遗传药理学(Pharmacogenetics);他莫昔芬(Tamoxifen)

DOI 10.1002/cpt.1007

PMID 29385237

发布时间 2024-08-29

基金项目

R24 GM061374/GM/NIGMS NIH HHS/United States R24 GM115264/GM/NIGMS NIH HHS/United States P50 CA116201/CA/NCI NIH HHS/United States R24 GM123930/GM/NIGMS NIH HHS/United States P50 GM115279/GM/NIGMS NIH HHS/United States

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