Overexpression of endothelin B receptor in glioblastoma: a prognostic marker and therapeutic target?

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作者： Suhas,Vasaikar ^[1] ; Giorgos,Tsipras ^[1] ; Natalia,Landázuri ^[1] ; Helena,Costa ^[2] ; Vanessa,Wilhelmi ^[2] ; Patrick,Scicluna ^[2] ; Huanhuan L,Cui ^[2] ; Abdul-Aleem,Mohammad ^[2] ; Belghis,Davoudi ^[2] ; Mingmei,Shang ^[1] ; Sharan,Ananthaseshan ^[2] ; Klas,Strååt ^[3] ; Giuseppe,Stragliotto ^[4] ; Afsar,Rahbar ^[2] ; Kum Thong,Wong ^[5] ; Jesper,Tegner ^[1] ; Koon-Chu,Yaiw ^[6] ; Cecilia,Söderberg-Naucler ^[7]

作者单位： Unit of Computational Medicine, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden. ^[1] Cell and Molecular Immunology, Experimental Cardiovascular Unit, Departments of Medicine and Neurology, Center for Molecular Medicine, Karolinska Institutet, SE-171 76, Stockholm, Sweden. ^[2] Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden. ^[3] Department of Neurosurgery, Karolinska University Hospital, Stockholm, Sweden. ^[4] Department of Pathology, University of Malaya, Kuala Lumpur, Malaysia. ^[5] Biological and Environmental Sciences and Engineering Division (BESE), Computer, Electrical and Mathematical Sciences and Engineering Division (CEMSE), King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia. ^[6] Cell and Molecular Immunology, Experimental Cardiovascular Unit, Departments of Medicine and Neurology, Center for Molecular Medicine, Karolinska Institutet, SE-171 76, Stockholm, Sweden. ykcywx@yahoo.com. ^[7] Cell and Molecular Immunology, Experimental Cardiovascular Unit, Departments of Medicine and Neurology, Center for Molecular Medicine, Karolinska Institutet, SE-171 76, Stockholm, Sweden. Cecilia.Naucler@ki.se. ^[8]

关键词 Endothelin B receptor Endothelin receptor antagonists Glioblastoma