首页> The Journal of allergy and clinical immunology> Autophagic dysfunction in patients with Papillon-Lefèvre syndrome is restored by recombinant cathepsin C treatment.

Autophagic dysfunction in patients with Papillon-Lefèvre syndrome is restored by recombinant cathepsin C treatment.

导出原文传递

翻译打印收藏纠错

第一作者： Pedro,Bullón

第一单位： Research Laboratory, Dental School, University of Sevilla, Seville, Spain; Department of Periodontology, Dental School, University of Sevilla, Seville, Spain.

作者： Pedro,Bullón ^[1] ; Beatriz,Castejón-Vega ^[2] ; Lourdes,Román-Malo ^[1] ; María Paz,Jimenez-Guerrero ^[3] ; David,Cotán ^[3] ; Tamara Y,Forbes-Hernandez ^[4] ; Alfonso,Varela-López ^[5] ; Antonio J,Pérez-Pulido ^[6] ; Francesca,Giampieri ^[4] ; José L,Quiles ^[5] ; Maurizio,Battino ^[4] ; José A,Sánchez-Alcázar ^[3] ; Mario D,Cordero ^[7]

作者单位： Research Laboratory, Dental School, University of Sevilla, Seville, Spain; Department of Periodontology, Dental School, University of Sevilla, Seville, Spain. ^[1] Research Laboratory, Dental School, University of Sevilla, Seville, Spain. ^[2] Centro Andaluz de Biología del Desarrollo (CABD), and Centro de Investigación Biomédica en Red: Enfermedades Raras, Instituto de Salud Carlos III, Consejo Superior de Investigaciones Científicas, Universidad Pablo de Olavide, Seville, Spain. ^[3] Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche, Sez. Biochimica, Università Politecnica delle Marche, Ancona, Italy. ^[4] Department of Physiology, Institute of Nutrition and Food Technology "José Mataix", Biomedical Research Center (CIBM), University of Granada, Armilla, Spain. ^[5] Centro Andaluz de Biología del Desarrollo (CABD), Universidad Pablo de Olavide-CSIC-Junta de Andalucía, Seville, Spain. ^[6] Department of Physiology, Institute of Nutrition and Food Technology "José Mataix", Biomedical Research Center (CIBM), University of Granada, Armilla, Spain. Electronic address: mdcormor@ugr.es. ^[7]

关键词 Papillon-Lefèvre syndrome autophagy cathepsin C lysosomal permeabilization