Evaluation of the clinical characteristics of everolimus-induced lung injury and determination of associated risk factors.

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作者： Mitsuhiro,Abe ^[1] ; Kenji,Tsushima ^[2] ; Jun,Ikari ^[3] ; Naoko,Kawata ^[4] ; Jiro,Terada ^[5] ; Nobuhiro,Tanabe ^[6] ; Koichiro,Tatsumi ^[7]

作者单位： Department of Respirology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan. Electronic address: mthrsgnm@yahoo.co.jp. ^[1] Department of Respirology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan. Electronic address: tsushimakenji@yahoo.co.jp. ^[2] Department of Respirology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan. Electronic address: junikari@chiba-u.jp. ^[3] Department of Respirology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan. Electronic address: chumito_03@yahoo.co.jp. ^[4] Department of Respirology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan. Electronic address: jirotera@chiba-u.jp. ^[5] Department of Respirology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan. Electronic address: ntanabe@faculty.chiba-u.jp. ^[6] Department of Respirology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan. Electronic address: tatsumi@faculty.chiba-u.jp. ^[7]

关键词 Drug-induced lung injury Everolimus Ground-glass opacity Krebs von den Lungen-6 Lactate dehydrogenase Mammalian target of rapamycin (mTOR)