换一批
换一批Osteoglycin attenuates cardiac fibrosis by suppressing cardiac myofibroblast proliferation and migration through antagonizing lysophosphatidic acid 3/matrix metalloproteinase 2/epidermal growth factor receptor signalling.
作者：
主题词
血管紧张素Ⅱ(Angiotensin II);动物(Animals);心脏扩大(Cardiomegaly);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);细胞, 培养的(Cells, Cultured);疾病模型, 动物(Disease Models, Animal);纤维化(Fibrosis);高血压(Hypertension);胞间信号肽类和蛋白质类(Intercellular Signaling Peptides and Proteins);基质金属蛋白酶14(Matrix Metalloproteinase 14);基质金属蛋白酶2(Matrix Metalloproteinase 2);小鼠, 近交C57BL(Mice, Inbred C57BL);丝裂原激活蛋白激酶类(Mitogen-Activated Protein Kinases);肌细胞, 心脏(Myocytes, Cardiac);肌成纤维细胞(Myofibroblasts);交叉感知受体(Receptor Cross-Talk);受体, 溶血磷脂酸(Receptors, Lysophosphatidic Acid);信号传导(Signal Transduction);心室重构(Ventricular Remodeling);ρGTP结合蛋白质类(rho GTP-Binding Proteins);rho相关激酶类(rho-Associated Kinases);ρA GTP结合蛋白质(rhoA GTP-Binding Protein)
DOI
10.1093/cvr/cvy035
PMID
29415171
发布时间
2020-12-09
- 浏览9
Cardiovascular research
703-712页
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