Osteopontin promotes metastasis of intrahepatic cholangiocarcinoma through recruiting MAPK1 and mediating Ser675 phosphorylation of β-Catenin.
第一作者:
Yan,Zheng
第一单位:
Department of General Surgery, Huashan Hospital & Cancer Metastasis Institute & Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
作者:
主题词
动物(Animals);胆管肿瘤(Bile Duct Neoplasms);病例对照研究(Case-Control Studies);细胞生长过程(Cell Growth Processes);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);胆管上皮癌(Cholangiocarcinoma);HEK293细胞(HEK293 Cells);人类(Humans);MAP激酶信号系统(MAP Kinase Signaling System);小鼠(Mice);小鼠, 裸(Mice, Nude);丝裂原活化蛋白激酶1(Mitogen-Activated Protein Kinase 1);肿瘤转移(Neoplasm Metastasis);骨桥蛋白质(Osteopontin);磷酰化(Phosphorylation);预后(Prognosis);丝氨酸(Serine);β连环素(beta Catenin)
DOI
10.1038/s41419-017-0226-x
PMID
29415992
发布时间
2023-04-11
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