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<i>C1orf106</i> is a colitis risk gene that regulates stability of epithelial adherens junctions.

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第一作者: Vishnu,Mohanan
第一单位: The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.;Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
作者单位: The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.;Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114, USA. [1] Montreal Heart Institute Research Center, Montreal, Quebec H1T 1C8, Canada. [2] Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114, USA. [3] The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. [4] Pathology Department, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.;Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Boston, MA 02114, USA. [5] Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Boston, MA 02114, USA.;Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA 02114, USA. [6] The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.;Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Boston, MA 02114, USA.;Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. [7] Montreal Heart Institute Research Center, Montreal, Quebec H1T 1C8, Canada.;Department of Medicine, Université de Montréal, Montreal, Quebec H1T 1C8, Canada. [8] The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. klassen@broadinstitute.org xavier@molbio.mgh.harvard.edu.;Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114, USA. [9] The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. klassen@broadinstitute.org xavier@molbio.mgh.harvard.edu.;Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114, USA.;Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Boston, MA 02114, USA.;Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA 02114, USA.;Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. [10]
DOI 10.1126/science.aan0814
PMID 29420262
发布时间 2022-01-26
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