A rapidly acquired foraging-based working memory task, sensitive to hippocampal lesions, reveals age-dependent and age-independent behavioural changes in a mouse model of amyloid pathology.
第一作者:
Charles,Evans
第一单位:
School of Psychology, Cardiff University, Park Place, Cardiff CF10 3AT, UK; School of Pharmacy & Pharmaceutical Sciences, Cardiff University, King Edward VII Avenue, Cardiff CF10 3NB, UK.
作者:
医学主题词
年龄因素(Age Factors);阿尔茨海默病(Alzheimer Disease);淀粉样β蛋白前体(Amyloid beta-Protein Precursor);动物(Animals);行为, 动物(Behavior, Animal);疾病模型, 动物(Disease Models, Animal);探究行为(Exploratory Behavior);海马(Hippocampus);记忆, 短时(Memory, Short-Term);小鼠(Mice);小鼠, 转基因(Mice, Transgenic)
DOI
10.1016/j.nlm.2018.02.004
PMID
29425692
发布时间
2019-09-16
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