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首页> Steroids> Comparison of flavonoids and isoflavonoids to inhibit rat and human 11β-hydroxysteroid dehydrogenase 1 and 2.

Comparison of flavonoids and isoflavonoids to inhibit rat and human 11β-hydroxysteroid dehydrogenase 1 and 2.

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作者： Qiqi,Zhu ^[1] ; Fei,Ge ^[1] ; Yaoyao,Dong ^[1] ; Wei,Sun ^[1] ; Zhe,Wang ^[1] ; Yuanyuan,Shan ^[1] ; Ruijie,Chen ^[1] ; Jianliang,Sun ^[2] ; Ren-Shan,Ge ^[3]

作者单位： The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, PR China. ^[1] Department of Anesthesia, Hangzhou Hospital Affiliated to Nanjing Medical University, Hangzhou First People's Hospital, Hangzhou 310006, PR China. Electronic address: kyk@njmu.edu.cn. ^[2] The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, PR China. Electronic address: renshan_ge@wmu.edu.cn. ^[3]

关键词 11β-Hydroxysteroid dehydrogenase 1 11β-Hydroxysteroid dehydrogenase 2 Diabetes Flavonoid Glucocorticoid metabolism Isoflavonoids Steroidogenesis

主题词 11-β-羟甾脱氢酶1型(11-beta-Hydroxysteroid Dehydrogenase Type 1);11-β-羟甾脱氢酶2型(11-beta-Hydroxysteroid Dehydrogenase Type 2);动物(Animals);芹菜素(Apigenin);剂量效应关系, 药物(Dose-Response Relationship, Drug);酶抑制剂(Enzyme Inhibitors);类黄酮物质(Flavonoids);染料木黄酮(Genistein);人类(Humans);异黄酮类(Isoflavones);蛋白质构象(Protein Conformation);槲皮素(Quercetin);大鼠(Rats)

DOI 10.1016/j.steroids.2018.01.013

PMID 29425740

发布时间 2018-10-22

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