GS-9620 inhibits enterovirus 71 replication mainly through the NF-κB and PI3K-AKT signaling pathways.

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作者： Qian,Zhang ^[1] ; Binbin,Zhao ^[1] ; Xin,Chen ^[1] ; Nan,Song ^[1] ; Jing,Wu ^[1] ; Guangchao,Li ^[1] ; Pin,Yu ^[1] ; Yunlin,Han ^[1] ; Jiangning,Liu ^[2] ; Chuan,Qin ^[3]

作者单位： Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences (CAMS) & Comparative Medicine Centre, Peking Union Medical Collage (PUMC) & Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases, Key Laboratory of Human Disease Comparative Medicine Ministry of Health, Beijing, PR China. ^[1] Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences (CAMS) & Comparative Medicine Centre, Peking Union Medical Collage (PUMC) & Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases, Key Laboratory of Human Disease Comparative Medicine Ministry of Health, Beijing, PR China. Electronic address: ljn_zb03038@126.com. ^[2] Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences (CAMS) & Comparative Medicine Centre, Peking Union Medical Collage (PUMC) & Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases, Key Laboratory of Human Disease Comparative Medicine Ministry of Health, Beijing, PR China. Electronic address: qinchuan@pumc.edu.cn. ^[3]

关键词 Enterovirus 71 Foot and mouth disease GS-9620 Hand NF-κB and PI3K-AKT signaling pathways