Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer.

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作者： Kevin,Shee ^[1] ; Wei,Yang ^[1] ; John W,Hinds ^[1] ; Riley A,Hampsch ^[1] ; Frederick S,Varn ^[1] ; Nicole A,Traphagen ^[2] ; Kishan,Patel ^[1] ; Chao,Cheng ^[1] ; Nicole P,Jenkins ^[1] ; Arminja N,Kettenbach ^[2] ; Eugene,Demidenko ^[3] ; Philip,Owens ^[3] ; Anthony C,Faber ^[2] ; Todd R,Golub ^[4] ; Ravid,Straussman ^[5] ; Todd W,Miller ^[6]

作者单位： Department of Molecular and Systems Biology, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH. ^[1] Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Lebanon, NH. ^[2] Department of Biochemistry and Cell Biology, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH. ^[3] Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN. ^[4] Research Medicine, Veterans Affairs, Tennessee Valley Healthcare System, Nashville, TN. ^[5] VCU Philips Institute for Oral Health Research, School of Dentistry and Massey Cancer Center, Virginia Commonwealth University, Richmond, VA. ^[6] Broad Institute of MIT and Harvard, Cambridge, MA. ^[7] Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel. ^[8] Department of Molecular and Systems Biology, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH todd.w.miller@dartmouth.edu. ^[9] Comprehensive Breast Program, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH. ^[10]