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The bHLH Protein Nulp1 is Essential for Femur Development Via Acting as a Cofactor in Wnt Signaling in Drosophila.

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第一作者： Q,Zeng

第一单位： The Center for Heart Development, State Key Laboratory of Development Biology, Key Laboratory of MOE for Development Biology and Protein Chemistry, College of Life Sciences, Hunan Normal University, Changsha, Hunan 410081, China.

作者： Q,Zeng ^[1] ; Y,Wan ^[1] ; P,Zhu ^[2] ; M,Zhao ^[3] ; F,Jiang ^[1] ; J,Chen ^[2] ; M,Tang ^[1] ; X,Zhu ^[2] ; Y,Li ^[1] ; H,Zha ^[1] ; Y,Wang ^[1] ; M,Hu ^[1] ; X,Mo ^[1] ; Y,Zhang ^[1] ; Y,Chen ^[1] ; Y,Chen ^[1] ; X,Ye ^[1] ; R,Bodmer ^[4] ; K,Ocorr ^[4] ; Z,Jiang ^[1] ; J,Zhuang ^[2] ; W,Yuan ^[1] ; X,Wu ^[1]

作者单位： The Center for Heart Development, State Key Laboratory of Development Biology, Key Laboratory of MOE for Development Biology and Protein Chemistry, College of Life Sciences, Hunan Normal University, Changsha, Hunan 410081, China. ^[1] Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510100, China. ^[2] Department of Pediatrics, the Third Xiangya Hospital, Central South University, Changsha, 410013, China. ^[3] Development, Aging and Regeneration Program, Sanford-Burnham-Prebys Medical Discovery Institute, La Jolla, CA 92037, United States. ^[4]

关键词 CRISPR/Cas9 Drosophila.Wnt/Wg signaling bHLH dNulp1 femur