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Systemic administration of donepezil attenuates the efficacy of environmental enrichment on neurobehavioral outcome after experimental traumatic brain injury.

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第一作者： Corina O,Bondi

第一单位： Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA.;Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, PA, USA.;Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.;Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA.

作者： Corina O,Bondi ^[1] ; Narayana K,Yelleswarapu ^[2] ; Julian,Day-Cooney ^[2] ; Kimiya,Memarzadeh ^[2] ; Kaitlin A,Folweiler ^[2] ; Carine E,Bou-Abboud ^[2] ; Jacob B,Leary ^[2] ; Jeffrey P,Cheng ^[2] ; Roya,Tehranian-DePasquale ^[2] ; Anthony E,Kline ^[3]

作者单位： Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA.;Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, PA, USA.;Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.;Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA. ^[1] Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA.;Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, PA, USA. ^[2] Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA.;Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, PA, USA.;Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA.;Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA, USA.;Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA.;Psychology, University of Pittsburgh, Pittsburgh, PA, USA. ^[3]

关键词 Beam-walking Morris water maze behavior controlled cortical impact (CCI)donepezil functional recovery hippocampus learning and memory traumatic brain injury