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Probing the Mechanism of Inactivation of the FOX-4 Cephamycinase by Avibactam.

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第一作者： Michiyoshi,Nukaga

第一单位： Department of Pharmaceutical Sciences, Josai International University, Togane City, Chiba, Japan.

作者： Michiyoshi,Nukaga ^[1] ; Krisztina M,Papp-Wallace ^[2] ; Tyuji,Hoshino ^[3] ; Scott T,Lefurgy ^[4] ; Christopher R,Bethel ^[5] ; Melissa D,Barnes ^[6] ; Elise T,Zeiser ^[5] ; J Kristie,Johnson ^[7] ; Robert A,Bonomo ^[8]

作者单位： Department of Pharmaceutical Sciences, Josai International University, Togane City, Chiba, Japan. ^[1] Research Service, Louis Stokes Cleveland Department of Veterans Affairs, Cleveland, Ohio, USA krisztina.papp@va.gov robert.bonomo@va.gov.;Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.;Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio, USA. ^[2] Graduate School of Pharmaceutical Sciences, Chiba University, Chuo-ku, Chiba, Japan. ^[3] Department of Chemistry, Hofstra University, Hempstead, New York, USA. ^[4] Research Service, Louis Stokes Cleveland Department of Veterans Affairs, Cleveland, Ohio, USA. ^[5] Research Service, Louis Stokes Cleveland Department of Veterans Affairs, Cleveland, Ohio, USA.;Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA. ^[6] Department of Pathology, University of Maryland, Baltimore, Maryland, USA. ^[7] Research Service, Louis Stokes Cleveland Department of Veterans Affairs, Cleveland, Ohio, USA krisztina.papp@va.gov robert.bonomo@va.gov.;Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.;Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, Ohio, USA.;Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, USA. ^[8]

关键词 avibactam beta-lactam beta-lactamase cephamycinase