PEAK1, acting as a tumor promoter in colorectal cancer, is regulated by the EGFR/KRas signaling axis and miR-181d.
作者:
主题词
动物(Animals);Caco-2细胞(Caco-2 Cells);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);结直肠肿瘤(Colorectal Neoplasms);女(雌)性(Female);基因表达调控, 酶学(Gene Expression Regulation, Enzymologic);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);HCT116细胞(HCT116 Cells);HT29细胞(HT29 Cells);人类(Humans);男(雄)性(Male);小鼠, 裸(Mice, Nude);微RNAs(MicroRNAs);中年人(Middle Aged);肿瘤侵润(Neoplasm Invasiveness);蛋白酪氨酸激酶类(Protein-Tyrosine Kinases);原癌基因蛋白质类p21(ras)(Proto-Oncogene Proteins p21(ras));信号传导(Signal Transduction)
DOI
10.1038/s41419-018-0320-8
PMID
29449544
发布时间
2020-04-08
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