换一批Celastrol pretreatment attenuates rat myocardial ischemia/ reperfusion injury by inhibiting high mobility group box 1 protein expression via the PI3K/Akt pathway.
第一作者：
Suiyang,Tong
第一单位：
Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, Hubei, PR China; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
作者：
医学主题词
动物(Animals);细胞凋亡(Apoptosis);HMGB1蛋白质(HMGB1 Protein);男(雄)性(Male);心肌再灌注损伤(Myocardial Reperfusion Injury);心肌(Myocardium);氧化性应激(Oxidative Stress);五环三萜类(Pentacyclic Triterpenes);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);预防和防护用药(Protective Agents);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);信号传导(Signal Transduction);三萜类(Triterpenes)
DOI
10.1016/j.bbrc.2018.02.121
PMID
29475002
发布时间
2021-12-04
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