The anaplerotic node is essential for the intracellular survival of <i>Mycobacterium tuberculosis</i>.

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作者： Piyali,Basu ^[1] ; Noor,Sandhu ^[1] ; Apoorva,Bhatt ^[2] ; Albel,Singh ^[2] ; Ricardo,Balhana ^[1] ; Irene,Gobe ^[1] ; Nicola A,Crowhurst ^[1] ; Tom A,Mendum ^[1] ; Liang,Gao ^[3] ; Jane L,Ward ^[3] ; Michael H,Beale ^[3] ; Johnjoe,McFadden ^[1] ; Dany J V,Beste ^[4]

作者单位： From the Department of Microbial and Cellular Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH. ^[1] the School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, and. ^[2] the Department of Computational and Analytical Sciences, Rothamsted Research, Harpenden, Herts AL5 2JQ, United Kingdom. ^[3] From the Department of Microbial and Cellular Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, d.beste@surrey.ac.uk. ^[4]

关键词 Microbial metabolism Mycobacterium tuberculosis enzyme gluconeogenesis host-pathogen interaction microbial pathogenesis microbiology tuberculosis

主题词细菌蛋白质类(Bacterial Proteins);人类(Humans);巨噬细胞(Macrophages);微生物生存能力(Microbial Viability);结核分枝杆菌(Mycobacterium tuberculosis)

DOI 10.1074/jbc.RA118.001839

PMID 29475946

发布时间 2021-02-05

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