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Assessment of the Genetic Architecture of Alzheimer's Disease Risk in Rate of Memory Decline.

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第一作者： Jorge L,Del-Aguila

第一单位： Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.;Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.

作者： Jorge L,Del-Aguila ^[1] ; Maria Victoria,Fernández ^[1] ; Suzanne,Schindler ^[2] ; Laura,Ibanez ^[1] ; Yuetiva,Deming ^[1] ; Shengmei,Ma ^[1] ; Ben,Saef ^[1] ; Kathleen,Black ^[1] ; John,Budde ^[1] ; Joanne,Norton ^[1] ; Rachel,Chasse ^[1] ; Alzheimer’s Disease Neuroimaging Initiative (ADNI) ^[3] ; Oscar,Harari ^[4] ; Alison,Goate ^[5] ; Chengjie,Xiong ^[2] ; John C,Morris ^[6] ; Carlos,Cruchaga

作者单位： Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.;Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. ^[1] Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.;Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA. ^[2] Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA. ^[3] Mount Sinai School of Medicine, New York, NY, USA. ^[4] Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA. ^[5] Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.;Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.;Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA. ^[6]

关键词 Alzheimer’s disease risk Clinical Dementia Rating sum of boxes International Genomics of Alzheimer’s Project (IGAP)polygenic risk score progression