Evaluation of a method for measuring the radioprotective metabolite WR-1065 in plasma using chemical derivatization combined with UHPLC-MS/MS.

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作者： Eric S,Simon ^[1] ; Dawn,Reyna ^[2] ; Richard J,Lister ^[2] ; Cheryl,Harteg ^[2] ; Elke,Lipka ^[2]

作者单位： TSRL, Inc., Ann Arbor, MI 48108, United States. Electronic address: esimon@tsrlinc.com. ^[1] TSRL, Inc., Ann Arbor, MI 48108, United States. ^[2]

主题词动物(Animals);色谱法, 高压液相(Chromatography, High Pressure Liquid);药物稳定性(Drug Stability);线性模型(Linear Models);男(雄)性(Male);巯基乙胺类(Mercaptoethylamines);辐射防护剂(Radiation-Protective Agents);大鼠(Rats);结果可重复性(Reproducibility of Results);敏感性与特异性(Sensitivity and Specificity);串联质谱法(Tandem Mass Spectrometry)

DOI 10.1016/j.jchromb.2018.02.030

PMID 29482122

发布时间 2021-11-19

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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

2018年1080卷

82-89页

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Evaluation of a method for measuring the radioprotective metabolite WR-1065 in plasma using chemical derivatization combined with UHPLC-MS/MS.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

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Evaluation of a method for measuring the radioprotective metabolite WR-1065 in plasma using chemical derivatization combined with UHPLC-MS/MS.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

相似文献

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

相关期刊

检索历史清除