Increasing the efficiency of clinical trials in neurodegenerative disorders using group sequential trial designs.
第一作者:
Ruben P A,van Eijk
第一单位:
Department of Neurology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.
作者:
医学主题词
肌萎缩侧索硬化(Amyotrophic Lateral Sclerosis);中枢神经系统药物(Central Nervous System Agents);置信区间(Confidence Intervals);临床试验早期终止(Early Termination of Clinical Trials);人类(Humans);医疗无效(Medical Futility);神经变性疾病(Neurodegenerative Diseases);安慰剂(Placebos);随机对照试验(主题)(Randomized Controlled Trials as Topic);研究设计(Research Design);时间因素(Time Factors)
DOI
10.1016/j.jclinepi.2018.02.013
PMID
29486281
发布时间
2019-09-09
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