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A Genetic Polymorphism in <i>CTLA-4</i> Is Associated with Overall Survival in Sunitinib-Treated Patients with Clear Cell Metastatic Renal Cell Carcinoma.

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作者单位: Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, the Netherlands. [1] Institute of Clinical Pharmacology, Qilu Hospital of Shandong University, Jinan, China. [2] Department of Clinical Pharmacy and Toxicology, Maastricht University Medical Center, Maastricht, the Netherlands. [3] Department of Medical Oncology, VU University Medical Center, Amsterdam, the Netherlands. [4] Oncology Department, Hospital Universitario 12 de Octubre, Madrid, Spain. [5] Department of Medical Oncology, Leiden University Medical Center, Leiden, the Netherlands. [6] Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands. [7] Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands. [8] Department of Urology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands. [9] Clinic of Urology and Paediatric Urology, Saarland University, Homburg, Germany. [10] CESAR Central Office, CESAR Central European Society for Anticancer Drug Research-EWIV, Vienna, Austria. [11] Department of Medicine, Landspitali-University Hospital, Reykjavik, Iceland. [12] Department of Oncology, Landspitali-University Hospital, Reykjavik, Iceland. [13] University of Medicine and Pharmacy Carol Davila, Bucuresti, Romania. [14] Department of Oncology, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge Biomedical Campus, Cambridge, United Kingdom. [15] Department of Pathology, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge Biomedical Campus, Cambridge, United Kingdom. [16] Hereditary Endocrine Cancer Group, Spanish National Cancer Research Centre (CNIO) and Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain. [17] Medical Oncology, HM Hospitales, Centro Integral Oncológico HM Clara Campal, Madrid, Spain. [18] Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands. [19] Department of Solid Tumor Oncology, Cleveland Clinic Taussig Cancer Institute (CCF), Cleveland, Ohio. [20] Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, the Netherlands. H.J.Guchelaar@lumc.nl. [21]
DOI 10.1158/1078-0432.CCR-17-2815
PMID 29490989
发布时间 2019-12-20
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Clinical cancer research : an official journal of the American Association for Cancer Research

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