首页> Oncotarget> Notoginsenoside R1 ameliorates diabetic encephalopathy by activating the Nrf2 pathway and inhibiting NLRP3 inflammasome activation.

Notoginsenoside R1 ameliorates diabetic encephalopathy by activating the Nrf2 pathway and inhibiting NLRP3 inflammasome activation.

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第一作者： Yadong,Zhai

第一单位： Beijing Key Laboratory of Innovative Drug Discovery of Traditional Chinese Medicine (Natural Medicine) and Translational Medicine, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.;Key Laboratory of Bioactive Substances and Resource Utilization of Chinese Herbal Medicine, Ministry of Education, Beijing, China.;Key Laboratory of Efficacy Evaluation of Chinese Medicine Against Glycolipid Metabolic Disorders, State Administration of Traditional Chinese Medicine, Beijing, China.

作者： Yadong,Zhai ^[1] ; Xiangbao,Meng ^[1] ; Yun,Luo ^[1] ; Yongmei,Wu ^[2] ; Tianyuan,Ye ^[1] ; Ping,Zhou ^[1] ; Shilan,Ding ^[1] ; Min,Wang ^[3] ; Senbao,Lu ^[4] ; Lili,Zhu ^[5] ; Guibo,Sun ^[1] ; Xiaobo,Sun ^[1]

作者单位： Beijing Key Laboratory of Innovative Drug Discovery of Traditional Chinese Medicine (Natural Medicine) and Translational Medicine, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.;Key Laboratory of Bioactive Substances and Resource Utilization of Chinese Herbal Medicine, Ministry of Education, Beijing, China.;Key Laboratory of Efficacy Evaluation of Chinese Medicine Against Glycolipid Metabolic Disorders, State Administration of Traditional Chinese Medicine, Beijing, China. ^[1] Department of Pharmacology, Changchun University of Traditional Chinese Medicine, Changchun, China. ^[2] College of Pharmacy, Harbin University of Commerce, Harbin, China. ^[3] Department of Bioengineering, Santa Clara University, Santa Clara, California, USA. ^[4] Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China. ^[5]

关键词 NLRP3 inflammasome Notoginsenoside R1 Nrf2 pathway diabetic encephalopathy oxidative stress

DOI 10.18632/oncotarget.24295

PMID 29507694

发布时间 2019-11-20

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