Impact of CYP2C19 Polymorphisms on Clinical Outcomes and Antiplatelet Potency of Clopidogrel in Caucasian Poststroke Survivors.

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第一作者： Aleš,Tomek

第一单位： Department of Neurology, 2nd Faculty of Medicine, Charles University, Prague and Motol University Hospital, Prague, Czech Republic.;Molecular Genetics Laboratory, Hospital Na Homolce, Prague, Czech Republic.

作者： Aleš,Tomek ^[1] ; Václav,Matʼoška ^[2] ; Alena,Frýdmanová ^[3] ; Hana,Magerová ^[4] ; Martin,Šrámek ^[4] ; Jaroslava,Paulasova-Schwabová ^[4] ; Tereza,Růžičková ^[4] ; Petr,Janský ^[4] ; Ivana,Šarbochová ^[4] ; Ivana,Hadačová ^[5] ; Vojtěch,Kaplan ^[2] ; Zuzana,Lacinová ^[2] ; Luděk,Táborský ^[2] ; Victor,Serebruany ^[6]

作者单位： Department of Neurology, 2nd Faculty of Medicine, Charles University, Prague and Motol University Hospital, Prague, Czech Republic.;Molecular Genetics Laboratory, Hospital Na Homolce, Prague, Czech Republic. ^[1] Molecular Genetics Laboratory, Hospital Na Homolce, Prague, Czech Republic. ^[2] Faculty of Pharmacology, Veterinary University Brno, Brno, Czech Republic. ^[3] Department of Neurology, 2nd Faculty of Medicine, Charles University, Prague and Motol University Hospital, Prague, Czech Republic. ^[4] Department of Hematology, 2nd Faculty of Medicine, Charles University, Prague and Motol University Hospital, Prague, Czech Republic. ^[5] Department of Neurology, Johns Hopkins University, Baltimore, MD. ^[6]

主题词年龄因素(Age Factors);老年人(Aged);女(雌)性(Female);基因型(Genotype);杂合子(Heterozygote);人类(Humans);脑缺血发作, 短暂性(Ischemic Attack, Transient);男(雄)性(Male);中年人(Middle Aged);心肌梗死(Myocardial Infarction);血小板聚集(Platelet Aggregation);血小板聚集抑制剂(Platelet Aggregation Inhibitors);多态现象, 遗传(Polymorphism, Genetic);回顾性研究(Retrospective Studies);危险性评估(Risk Assessment);卒中(Stroke);幸存患者(Survivors);噻氯匹定(Ticlopidine);治疗结果(Treatment Outcome)

DOI 10.1097/MJT.0000000000000416

PMID 29509167

发布时间 2022-12-07

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American journal of therapeutics

e202-e212页

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Impact of CYP2C19 Polymorphisms on Clinical Outcomes and Antiplatelet Potency of Clopidogrel in Caucasian Poststroke Survivors.

American journal of therapeutics

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American journal of therapeutics

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Impact of CYP2C19 Polymorphisms on Clinical Outcomes and Antiplatelet Potency of Clopidogrel in Caucasian Poststroke Survivors.

American journal of therapeutics

相似文献

American journal of therapeutics

相关期刊

检索历史清除