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Validation of a 10-gene molecular signature for predicting biochemical recurrence and clinical metastasis in localized prostate cancer.

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第一作者： Hatem,Abou-Ouf

第一单位： Department of Pathology and Laboratory Medicine, University of Calgary, Cumming School of Medicine, Calgary, AB, Canada.;Calgary Laboratory Services, Calgary, AB, Canada.

作者： Hatem,Abou-Ouf ^[1] ; Mohammed,Alshalalfa ^[2] ; Mandeep,Takhar ^[2] ; Nicholas,Erho ^[2] ; Bryan,Donnelly ^[3] ; Elai,Davicioni ^[2] ; R Jeffrey,Karnes ^[4] ; Tarek A,Bismar ^[5]

作者单位： Department of Pathology and Laboratory Medicine, University of Calgary, Cumming School of Medicine, Calgary, AB, Canada.;Calgary Laboratory Services, Calgary, AB, Canada. ^[1] Genome DX Biosciences, San Diego, CA, USA. ^[2] Department of Urology, University of Calgary, Calgary, AB, Canada. ^[3] Department of Urology, Mayo Clinic, Rochester, MN, USA. ^[4] Department of Pathology and Laboratory Medicine, University of Calgary, Cumming School of Medicine, Calgary, AB, Canada. tabismar@ucalgary.ca.;Calgary Laboratory Services, Calgary, AB, Canada. tabismar@ucalgary.ca.;Department of Oncology, University of Calgary, Calgary, AB, Canada. tabismar@ucalgary.ca.;Arnie Charbonneau Cancer Institute and Tom Baker Cancer Center, Calgary, AB, Canada. tabismar@ucalgary.ca.;Rockyview General Hospital, Department of Pathology, Calgary Laboratory Services, 7007 - 14th Street SW, Calgary, AB, T2V 1P9, Canada. tabismar@ucalgary.ca. ^[5]

关键词 Biochemical recurrence Biomarkers Clinical metastasis Genetic classifier Gleason score Grade grouping Prognosis Prostate cancer