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Chronic stress promotes colitis by disturbing the gut microbiota and triggering immune system response.

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第一作者： Xinghua,Gao

第一单位： State Key Laboratory of Natural Medicines, China Pharmaceutical University, 211198 Nanjing, China.;Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, 211198 Nanjing, China.;Center for New Drug Safety Evaluation and Research, China Pharmaceutical University, 211198 Nanjing, China.

作者： Xinghua,Gao ^[1] ; Qiuhua,Cao ^[1] ; Yan,Cheng ^[1] ; Dandan,Zhao ^[1] ; Zhuo,Wang ^[2] ; Hongbao,Yang ^[1] ; Qijin,Wu ^[1] ; Linjun,You ^[1] ; Yue,Wang ^[1] ; Yanting,Lin ^[1] ; Xianjing,Li ^[1] ; Yun,Wang ^[1] ; Jin-Song,Bian ^[3] ; Dongdong,Sun ^[4] ; Lingyi,Kong ^[1] ; Lutz,Birnbaumer ^[5] ; Yong,Yang ^[6]

作者单位： State Key Laboratory of Natural Medicines, China Pharmaceutical University, 211198 Nanjing, China.;Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, 211198 Nanjing, China.;Center for New Drug Safety Evaluation and Research, China Pharmaceutical University, 211198 Nanjing, China. ^[1] State Key Laboratory of Natural Medicines, China Pharmaceutical University, 211198 Nanjing, China.;Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, 211198 Nanjing, China.;Center for New Drug Safety Evaluation and Research, China Pharmaceutical University, 211198 Nanjing, China.;Translational Medicine Center, Nanjing University of Chinese Medicine, 210023 Nanjing, China. ^[2] Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 117597 Singapore. ^[3] Translational Medicine Center, Nanjing University of Chinese Medicine, 210023 Nanjing, China. ^[4] Neurobiology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709; birnbau1@gmail.com yy@cpu.edu.cn.;Biomedical Research Institute, Catholic University of Argentina, C1107AAZ Buenos Aires, Argentina. ^[5] State Key Laboratory of Natural Medicines, China Pharmaceutical University, 211198 Nanjing, China; birnbau1@gmail.com yy@cpu.edu.cn.;Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, 211198 Nanjing, China.;Center for New Drug Safety Evaluation and Research, China Pharmaceutical University, 211198 Nanjing, China. ^[6]

关键词 DSS-induced colitis chronic stress gut microbiota immune reaction mucin-2