换一批
第一作者：
David,Capper
第一单位：
Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.;Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.;Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Neuropathology, Berlin, Germany.;German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany.
作者：
David,Capper [1]
;
David T W,Jones [2]
;
Martin,Sill [3]
;
Volker,Hovestadt [4]
;
Daniel,Schrimpf [5]
;
Dominik,Sturm [6]
;
Christian,Koelsche [5]
;
Felix,Sahm [5]
;
Lukas,Chavez [2]
;
David E,Reuss [5]
;
Annekathrin,Kratz [5]
;
Annika K,Wefers [5]
;
Kristin,Huang [5]
;
Kristian W,Pajtler [6]
;
Leonille,Schweizer [7]
;
Damian,Stichel [5]
;
Adriana,Olar [8]
;
Nils W,Engel [9]
;
Kerstin,Lindenberg [10]
;
Patrick N,Harter [11]
;
Anne K,Braczynski [11]
;
Karl H,Plate [11]
;
Hildegard,Dohmen [12]
;
Boyan K,Garvalov [12]
;
Roland,Coras [13]
;
Annett,Hölsken [13]
;
Ekkehard,Hewer [14]
;
Melanie,Bewerunge-Hudler [15]
;
Matthias,Schick [15]
;
Roger,Fischer [15]
;
Rudi,Beschorner [16]
;
Jens,Schittenhelm [16]
;
Ori,Staszewski [17]
;
Khalida,Wani [18]
;
Pascale,Varlet [19]
;
Melanie,Pages [19]
;
Petra,Temming [20]
;
Dietmar,Lohmann [21]
;
Florian,Selt [22]
;
Hendrik,Witt [6]
;
Till,Milde [22]
;
Olaf,Witt [22]
;
Eleonora,Aronica [23]
;
Felice,Giangaspero [24]
;
Elisabeth,Rushing [25]
;
Wolfram,Scheurlen [26]
;
Christoph,Geisenberger [27]
;
Fausto J,Rodriguez [28]
;
Albert,Becker [29]
;
Matthias,Preusser [30]
;
Christine,Haberler [31]
;
Rolf,Bjerkvig [32]
;
Jane,Cryan [33]
;
Michael,Farrell [33]
;
Martina,Deckert [34]
;
Jürgen,Hench [35]
;
Stephan,Frank [35]
;
Jonathan,Serrano [36]
;
Kasthuri,Kannan [36]
;
Aristotelis,Tsirigos [36]
;
Wolfgang,Brück [37]
;
Silvia,Hofer [38]
;
Stefanie,Brehmer [39]
;
Marcel,Seiz-Rosenhagen [39]
;
Daniel,Hänggi [39]
;
Volkmar,Hans [40]
;
Stephanie,Rozsnoki [41]
;
Jordan R,Hansford [42]
;
Patricia,Kohlhof [43]
;
Bjarne W,Kristensen [44]
;
Matt,Lechner [45]
;
Beatriz,Lopes [46]
;
Christian,Mawrin [47]
;
Ralf,Ketter [48]
;
Andreas,Kulozik [49]
;
Ziad,Khatib [50]
;
Frank,Heppner [51]
;
Arend,Koch [52]
;
Anne,Jouvet [53]
;
Catherine,Keohane [54]
;
Helmut,Mühleisen [55]
;
Wolf,Mueller [56]
;
Ute,Pohl [57]
;
Marco,Prinz [58]
;
Axel,Benner [59]
;
Marc,Zapatka [4]
;
Nicholas G,Gottardo [60]
;
Pablo Hernáiz,Driever [61]
;
Christof M,Kramm [62]
;
Hermann L,Müller [63]
;
Stefan,Rutkowski [64]
;
Katja,von Hoff [65]
;
Michael C,Frühwald [66]
;
Astrid,Gnekow [66]
;
Gudrun,Fleischhack [20]
;
Stephan,Tippelt [20]
;
Gabriele,Calaminus [67]
;
Camelia-Maria,Monoranu [68]
;
Arie,Perry [69]
;
Chris,Jones [70]
;
Thomas S,Jacques [71]
;
Bernhard,Radlwimmer [4]
;
Marco,Gessi [29]
;
Torsten,Pietsch [29]
;
Johannes,Schramm [72]
;
Gabriele,Schackert [73]
;
Manfred,Westphal [74]
;
Guido,Reifenberger [75]
;
Pieter,Wesseling [76]
;
Michael,Weller [77]
;
Vincent Peter,Collins [78]
;
Ingmar,Blümcke [13]
;
Martin,Bendszus [79]
;
Jürgen,Debus [80]
;
Annie,Huang [81]
;
Nada,Jabado [82]
;
Paul A,Northcott [83]
;
Werner,Paulus [41]
;
Amar,Gajjar [84]
;
Giles W,Robinson [84]
;
Michael D,Taylor [85]
;
Zane,Jaunmuktane [86]
;
Marina,Ryzhova [87]
;
Michael,Platten [88]
;
Andreas,Unterberg [89]
;
Wolfgang,Wick [90]
;
Matthias A,Karajannis [91]
;
Michel,Mittelbronn [92]
;
Till,Acker [12]
;
Christian,Hartmann [93]
;
Kenneth,Aldape [94]
;
Ulrich,Schüller [95]
;
Rolf,Buslei [96]
;
Peter,Lichter [4]
;
Marcel,Kool [2]
;
Christel,Herold-Mende [89]
;
David W,Ellison [97]
;
Martin,Hasselblatt [41]
;
Matija,Snuderl [98]
;
Sebastian,Brandner [99]
;
Andrey,Korshunov [5]
;
Andreas,von Deimling [5]
;
Stefan M,Pfister [6]
作者单位：
Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.;Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.;Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Neuropathology, Berlin, Germany.;German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany.
[1]
Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.;Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
[2]
Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.;Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.;Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
[3]
Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
[4]
Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.;Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
[5]
Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.;Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.;Department of Pediatric Oncology, Hematology and Immunology, University Hospital Heidelberg, Heidelberg, Germany.
[6]
Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.;Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Neuropathology, Berlin, Germany.
[7]
Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina 29425, USA.;Department of Neurosurgery, Medical University of South Carolina, Charleston, South Carolina 29425, USA.;Hollings Cancer Center, Charleston, South Carolina 29425, USA.
[8]
Department of Oncology and Hematology with Sections Bone Marrow Transplant and Pneumology, Hubertus Wald Tumorzentrum/University Cancer Center Hamburg, University Medical Center Hamburg, Hamburg, Germany.;Center for Neuropathology and Prion Research, Ludwig-Maximilians-University, Munich, Germany.
[9]
Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
[10]
Institute of Neurology (Edinger Institute), Goethe-University Frankfurt am Main, Frankfurt am Main, Germany.;German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt am Main, German Cancer Research Center (DKFZ) Heidelberg, Germany.
[11]
Institute of Neuropathology, University of Giessen, Giessen, Germany.
[12]
Neuropathological Institute, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany.
[13]
Institute of Pathology, University of Bern, Bern, Switzerland.
[14]
Genomics and Proteomics Core Facility, German Cancer Research Center (DKFZ), Heidelberg, Germany.
[15]
Institute of Pathology and Neuropathology, Department of Neuropathology, University Hospital Tübingen, Tübingen, Germany.
[16]
Institute of Neuropathology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
[17]
Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
[18]
Department of Neuropathology, Centre Hospitalier Sainte Anne, Paris, France.
[19]
Pediatrics III, Pediatric Oncology and Hematology, University Hospital Essen, Essen, Germany.
[20]
Eye Cancer Research Group, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany.
[21]
Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.;Department of Pediatric Oncology, Hematology and Immunology, University Hospital Heidelberg, Heidelberg, Germany.;CCU Pediatric Oncology (G340), German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.
[22]
Department of (Neuro)Pathology, Academic Medisch Centrum (AMC), University of Amsterdam, Amsterdam, The Netherlands.;Swammerdam Institute for Life Sciences, Center for Neuroscience, University of Amsterdam, Amsterdam, The Netherlands.;Stichting Epilepsie Instellingen Nederland (SEIN), Amsterdam, The Netherlands.
[23]
Department of Radiological, Oncological and Anatomo-Pathological Sciences, Sapienza University, Rome, Italy.;IRCCS Neuromed, Pozzilli, Italy.
[24]
Department of Neuropathology, University Hospital Zurich, Zurich, Switzerland.
[25]
Cnopf'sche Kinderklinik Nuremberg, Nuremberg, Germany.
[26]
Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.;Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences), Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.
[27]
Division of Neuropathology of the Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
[28]
Department of Neuropathology, University of Bonn, Bonn, Germany.
[29]
Department of Medicine I, Comprehensive Cancer Center Vienna, CNS Unit (CCC-CNS), Medical University of Vienna, Vienna, Austria.
[30]
Institute of Neurology, Medical University of Vienna, Vienna, Austria.
[31]
Department of Biomedicine, University of Bergen, Bergen, Norway.;NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg, Luxembourg.
[32]
Department of Neuropathology, Beaumont Hospital, Dublin, Ireland.
[33]
Department of Neuropathology, University Hospital of Cologne, Cologne, Germany.
[34]
Department of Neuropathology, Institute of Pathology, Basel University Hospital, Basel, Switzerland.
[35]
NYU Langone Medical Center, New York, New York, USA.
[36]
Institute of Neuropathology, University Medical Center Göttingen, Göttingen, Germany.
[37]
Division of Oncology, Luzerner Kantonsspital, Luzern, Switzerland.
[38]
Department of Neurosurgery, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany.
[39]
Institut für Neuropathologie, Evangelisches Krankenhaus Bielefeld gGmbH, Bielefeld, Germany.;Institut für Neuropathologie, Universitätskinikum Essen, Essen, Germany.
[40]
Institute of Neuropathology, University Hospital Münster, Münster, Germany.
[41]
Children's Cancer Centre, Royal Children's Hospital, University of Melbourne, Melbourne, Victoria, Australia.;Murdoch Children's Research Institute, University of Melbourne, Melbourne, Victoria, Australia.;Department of Pediatrics, University of Melbourne, Melbourne, Victoria, Australia.
[42]
Institute for Pathology, Katharinenhospital Stuttgart, Stuttgart, Germany.
[43]
Department of Pathology, Odense University Hospital, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
[44]
University College London Cancer Institute and University College London Hospitals, London, UK.
[45]
Department of Pathology, University of Virginia, Charlottesville, Virginia, USA.
[46]
Institute of Neuropathology, Otto-von-Guericke-University, Magdeburg, Germany.
[47]
Department of Neurosurgery, University Hospital Saarland, Homburg, Saar, Germany.
[48]
Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.;Department of Pediatric Oncology, Hematology and Immunology, University Hospital Heidelberg, Heidelberg, Germany.
[49]
Nicklaus Children's Hospital Brain Institute, Miami, Florida 33155, USA.
[50]
Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Neuropathology, Berlin, Germany.;Cluster of Excellence, NeuroCure, Berlin, Germany.;Berlin Institute of Health (BIH), Berlin, Germany.
[51]
Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Neuropathology, Berlin, Germany.
[52]
Département de Pathologie et Neuropathologie, Hôpital Neurologique, Hospices Civils de Lyon, Lyon, France.
[53]
Department of Neuropathology, Cork University Hospital, Cork, Ireland.
[54]
Department of Pathology, Ludwigsburg Hospital, Ludwigsburg, Germany.
[55]
Department of Neuropathology, Leipzig University, Leipzig, Germany.
[56]
Department of Cellular Pathology, Queen's Hospital, Romford, UK.
[57]
Institute of Neuropathology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.;BIOSS Centre for Biological Signalling Studies, University of Freiburg, Freiburg, Germany.
[58]
Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
[59]
Department of Pediatric Oncology and Haematology, Princess Margaret Hospital for Children, GPO Box D184, Perth, Western Australia 6840, Australia.;Telethon Kids Institute, University of Western Australia, PO Box 855, Perth, Western Australia 6872, Australia.;School of Paediatrics and Child Health, University of Western Australia, GPO Box D184, Perth, Western Australia 6840, Australia.
[60]
Department of Pediatric Oncology/Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
[61]
Division of Pediatric Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany.
[62]
Department of Pediatrics and Pediatric Hematology/Oncology, Klinikum Oldenburg AöR, Medical Campus University Oldenburg, 26133 Oldenburg, Germany.
[63]
Department for Pediatric Hematology and Oncology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
[64]
Department of Pediatric Oncology/Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany.;Department for Pediatric Hematology and Oncology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
[65]
Children's Hospital Augsburg, Swabian Children's Cancer Centre, Augsburg, Germany.
[66]
Department of Pediatric Hematology/Oncology, University of Bonn Medical Center, Bonn, Germany.
[67]
Department of Neuropathology, Insitute of Pathology, Comprehensive Cancer Center (CCC) Mainfranken, University of Würzburg, Würzburg, Germany.
[68]
Department of Pathology, University of California San Francisco, San Francisco, California, USA.
[69]
Division of Molecular Pathology, Institute of Cancer Research, London, UK.
[70]
Developmental Biology and Cancer Programme, UCL Great Ormond Street Institute of Child Health and Histopathology Department, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
[71]
Medical Faculty, University of Bonn Medical School, Bonn, Germany.
[72]
Department of Neurosurgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
[73]
Department of Neurosurgery, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
[74]
Department of Neuropathology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.;German Cancer Consortium (DKTK), partner site Essen/Düsseldorf, German Cancer Research Center (DKFZ), Heidelberg, Germany.
[75]
Department of Pathology, Princess Máxima Center for Pediatric Oncology and University Medical Center Utrecht, Utrecht, The Netherlands.;Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.
[76]
Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.
[77]
Department of Pathology, Division of Molecular Histopathology, University of Cambridge, Cambridge, UK.
[78]
Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany.
[79]
Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany.
[80]
Department of Pediatrics, Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
[81]
Division of Hematology/Oncology, McGill University, Montreal, Quebec, Canada.
[82]
Department of Developmental Neurobiology, St Jude Children's Research Hospital, Memphis, Tennessee, USA.
[83]
Department of Oncology, St Jude Children's Research Hospital, Memphis, Tennessee, USA.
[84]
Division of Neurosurgery, Arthur and Sonia Labatt Brain Tumor Research Centre, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
[85]
Division of Neuropathology, UCL Hospitals, Institute of Neurology, University College London, Queen Square, WC1N 3BG London, UK.;Department of Molecular Neuroscience, Institute of Neurology, University College London, Queen Square, WC1N 3BG London, UK.;Department of Neurodegeneration, Institute of Neurology, University College London, Queen Square, WC1N 3BG London, UK.
[86]
NN Burdenko Neurosurgical Institute, Moscow, Russia.
[87]
Department of Neurology, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
[88]
Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
[89]
Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany.
[90]
Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
[91]
Institute of Neurology (Edinger Institute), Goethe-University Frankfurt am Main, Frankfurt am Main, Germany.;German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt am Main, German Cancer Research Center (DKFZ) Heidelberg, Germany.;NORLUX Neuro-Oncology Laboratory, Luxembourg Institute of Health (LIH), Luxembourg, Luxembourg.;Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Luxembourg, Luxembourg.;Laboratoire national de santé (LNS), Dudelange, Luxembourg.;Luxembourg Centre of Neuropathology (LCNP), Luxembourg, Luxembourg.
[92]
Department of Neuropathology, Hannover Medical School (MHH), Hannover, Germany.
[93]
Department of Pathology, University of Toronto, Toronto, Ontario, Canada.
[94]
Center for Neuropathology and Prion Research, Ludwig-Maximilians-University, Munich, Germany.;Institute of Neuropathology, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany.;Research Institute Children's Cancer Center, Hamburg, Germany.;Department of Pediatric Hematology and Oncology, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany.
[95]
Neuropathological Institute, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany.;Section Neuropathology, Institute of Pathology, Sozialstiftung Bamberg, Klinikum am Bruderwald, Bamberg, Germany.
[96]
Department of Pathology, St Jude Children's Research Hospital, Memphis, Tennessee, USA.
[97]
Division of Neuropathology, Department of Pathology, NYU Langone Medical Center, New York, New York, USA.
[98]
Division of Neuropathology, UCL Hospitals, Institute of Neurology, University College London, Queen Square, WC1N 3BG London, UK.;Department of Neurodegeneration, Institute of Neurology, University College London, Queen Square, WC1N 3BG London, UK.
[99]
医学主题词
青少年(Adolescent);成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);中枢神经系统肿瘤(Central Nervous System Neoplasms);儿童(Child);儿童, 学龄前(Child, Preschool);队列研究(Cohort Studies);DNA甲基化(DNA Methylation);女(雌)性(Female);人类(Humans);婴儿(Infant);男(雄)性(Male);中年人(Middle Aged);结果可重复性(Reproducibility of Results);青年人(Young Adult)
DOI
10.1038/nature26000
PMID
29539639
发布时间
2025-05-30
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Nature
Nature
469-474页
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